The AndzonBio® model proposes a suite of Pipeline Builder Companies to accelerate the development of the most promising academic projects in life sciences.
AndzonBio® Pipeline Builder Companies are built on the conviction that focusing on specific therapeutic areas, combined with a hands-on, expert-driven approach, is the key to unlock the full potential of each academic project.
AndzonBio® Pipeline Builder Companies are built on the conviction that focusing on specific therapeutic areas, combined with a hands-on, expert-driven approach, is the key to unlock the full potential of each academic project.
With a dedicated leadership team of seasoned biotech professionals and a rich network of industry leaders, AndzonBio1 is ideally positioned to capture and develop well-differentiated and high-potential CVRM assets with:
• Rigorous process to select the most promising projects
• Leverage on an established network of world-leading experts and top tier CROs
• Comprehensive development plan
• Clear path to value generation and company growth
All academic projects identified and evaluated must have exceptional potential to contribute to building a pipeline of programs bringing breakthrough innovations developed by strong and recognized KOLs, new targets of interest and first-in-class therapy potential. Overall, eachcompany’s pipeline program shall contribute to addressing urgent unmet medical needs and be capable of meeting the interest of strategic partners.
100s of Millions
of people globally live
with CVRM disease
98% of patients
with type 2
diabetes have at least
one other CVRM disease
40-50% of patients
with heart failure have
chronic kidney disorders
CardioVascular, Renal & Metabolic diseases still represent a major unmet medical need and are the main leading cause of death globally due to several factors such as:
• High prevalence and co-morbidities: multiple prevalent diseases often coexist and exacerbate each other. For example, people with type 2 diabetes have a significantly higher risk of developing cardiovascular disease and chronic kidney disease. This interconnection creates a complex health burden
• Lifestyle factors: Unhealthy diets, lack of physical activity are prevalent risk factors that contribute to this spectrum of diseases. These lifestyle factors are difficult to manage on a global scale.
• Aging: As the global population ages, the incidence of these diseases increases. Older adults are more susceptible to CVRM disorders, leading to higher mortality rates.
• Insufficient medical progress: Despite clear advances in medical research, there are still gaps in effective treatments and preventive measures. The complexity of these diseases requires new and more integrated therapeutic approaches.
Addressing these challenges requires multifaceted approaches, including public health initiatives, lifestyle interventions, and continued biomedical research to develop more effective treatments and preventive strategies.
DIABETES
AFFECTS
410 MILLION
PEOPLE
WITH AN OVER
70%
INCREASE
IN FATALITIES
SINCE 2000
RESULTING IN
1.5 MILLION
DEATHS
PER YEAR
KIDNEY
DISEASE
AFFECTS
APPROXIMATELY
700 MILLION
PEOPLE
WITH A
40% INCREASE
IN PATIENTS NEEDING
DIALYSIS
IN FATALITIES
SINCE 2000
SINCE 1990
AND CAUSES
1.5 MILLION
DEATHS
PER YEAR
STROKES
CAUSE OVER
6.5 MILLION
DEATHS
PER YEAR
AND AFFECT
101 MILLION
PEOPLE
WITH CASES
ON THE RISE
HEART
DISEASE
IS BECOMING
MORE
PREVALENT
AFFECTING AROUND
26 MILLION
PEOPLE
AND CAUSING
9 MILLION
DEATHS
PER YEAR
LIVER
DISEASE
AFFECT
AN ESTIMATED
1.5 BILLION
PEOPLE
AND AS MANY AS
40% OF THE
ADULT POPULATION
IN SOME COUNTRIES
LEADING TO
2 MILLION
DEATHS
PER YEAR
From owlstone medical 2022
AndzonBio1 is relying on a leadership team composed of highly skilled biotech professionals with complementary expertise, and an outstanding Scientific Advisory Board composed of top-tier experts, bringing a strong blend of experience in Drug Development and CVRM expertise.
Vincent Bischoff
Vincent Bischoff
Chief Executive Officer
Sébastien Bolze
Sébastien Bolze
PharmD, PhD
Karine Charton
Karine Charton
Chief Operational Officer
Armelle Serose
Armelle Serose
Liaison Manager
Alexandre Jouve, PharmD
Alexandre Jouve, PharmD
Chief Financial Officer
Jean-François Arrighi
Jean-François Arrighi
PhD
Lars Erwig
Lars Erwig
PhD
Michael Motz
Michael Motz
CVRM and Drug Dev. expertise
Pascal Augé
Pascal Augé
Chair of the Board
Chair of the executive management board at Inserm Transfert
Alain Huriez
Alain Huriez
Acting Chief Executive Officer of AndzonBio1, Chair and managing partner at AdBio Partners
Noémie Pellegrin
Noémie Pellegrin
Director of Industry Partnerships and Entrepreneurship, Inserm Transfert
Clément Bertholet
Clément Bertholet
Partner at AdBio Partners
10, rue d’Oradour-sur-Glane
75015 Paris
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